A new case of sarcomatous degeneration of the spine in Paget's disease of bone
Villiaumey, J.; Di Menza, C.; Rotterdam, M.; Voisin, M.C.; Cherot, A.
Revue du Rhumatisme et des Maladies Osteo-Articulaires 42(11): 687-691
1975
ISSN/ISBN: 0035-2659 PMID: 1063431 Document Number: 88354
In referring to a personal observation the authors recall the rarity of malignant degeneration of lesions of the spine caused by Paget's disease. In the majority of cases these consist of multiple centred osteo-sarcomatosis. The lumbar spine is the most often affected. The clinical picture is essentially a syndrome of radiculomedullary compression. Rapid aggravation of the condition usually leads to a neurosurgical operation, which will confirm the existence of the osteo-sarcomatous process. The evolution is always fatal.