Stabilization of brain free polysomes by morphine
Stolman, S.; Loh, H.H.
Research Communications in Chemical Pathology and Pharmacology 12(3): 419-424
1975
ISSN/ISBN: 0034-5164 PMID: 1197923 Document Number: 88024
The effect of morphine on brain free polysomes prepared from mouse brain was studied. It was found that morphine binds to polysomes and protects them from disaggregation. The significance of this effect with respect to brain protein is discussed.
Document emailed within 1 workday
Related Documents
Jachymczyk, W.J.; Sieliwanowicz, B. 1971: The influence of basic proteins on polysomes. Studies on the reactivation of polysomes inhibited by histones in a cell-free system Acta Biochimica Polonica 18(2): 121-128Berman, A.E.; Oborotova, T.A.; Mazurov, V.I. 1972: Biosynthesis of collagen on free and bound polysomes Biokhimiia 37(3): 658-660
Jachymczyk, W.J.; Sieliwanowicz, B.; Zaleski, J. 1972: The influence of basic proteins on polysomes. the interaction of histones with rat liver polysomes Acta Biochimica Polonica 19(2): 117-123
Kogan, G.L.; Berman, A.E.; Mazurov, V.I. 1973: Collagen biosynthesis in a cell-free system in the presence of RNA isolated from the polysomes of chick embryos Biokhimiia 38(4): 872-874
Berman, A.E. 1975: Biosynthesis of collagen and non-collagen proteins on free and bound polysomes from chick embryo Biokhimiia 40(2): 432-440
Bickel, U.; Schumacher, O.P.; Kang, Y.S.; Voigt, K. 1996: Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat Journal of Pharmacology and Experimental Therapeutics 278(1): 107-113
Dockery, G.L.; Gusman, D.N.; Vickers, M.B. 1989: An autogenous free graft technique for lateral ankle stabilization Journal of Foot Surgery 28(4): 319-324
Rondinone, R. 1989: Fatty acids in the development and stabilization of the rat brain Bollettino della Societa Italiana di Biologia Sperimentale 65(3): 259-264
Satoh, M.; Wang, J.; Reeves, W.H. 1995: Role of free p70 (Ku) subunit in posttranslational stabilization of newly synthesized p80 during DNA-dependent protein kinase assembly European Journal of Cell Biology 66(2): 127-135
Mignat, C.; Jansen, R.; Ziegler, A. 1995: Plasma and cerebrospinal fluid concentrations of morphine and morphine glucuronides in rabbits receiving single and repeated doses of morphine Journal of Pharmacy and Pharmacology 47(2): 171-175
Uchihashi, Y.; Kuribara, H.; Morita, T.; Kitani, Y.; Karasawa, F.; Sato, T. 1996: Differential effects of morphine-6-glucuronide, an active metabolite of morphine, and morphine on locomotor activity in mice: involvement of the opioid receptor Pharmacology and Toxicology 78(5): 322-326
Shimada, M.; Kihara, T.; Kurimoto, K.; Maruyama, Y.; Ijichi, H. 1972: Topographic separation of lyophilized mouse brain and gas-liquid chromatographic analysis of free amino acids in brain divisions Kaibogaku Zasshi. Journal of Anatomy 47(2): 138-153
Consorti, D.; Castellano, C.; Oliverio, A.; Pavone, F. 1992: Length of social deprivation differently affects free-choice morphine consumption in C57BL/6J mice Functional Neurology 7(4): 299-303
Waikakul, S.; Harnroongroj, T.; Vanadurongwan, V. 1999: Immediate stabilization of unstable pelvic fractures versus delayed stabilization Journal of the Medical Association of Thailand 82(7): 637-642
Hula, N.M.; Marhitych, V.M.; Hovseieva, N.M.; Klimashevs'kyĭ, V.M.; Zhukov, O.D.; Synyts'kyĭ, V.M. 1998: Brain lipid composition of the rat with experimental morphine dependence Ukrainskii Biokhimicheskii Zhurnal 70(2): 98-105
Van Crugten, J.T.; Sallustio, B.C.; Nation, R.L.; Somogyi, A.A. 1991: Renal tubular transport of morphine, morphine-6-glucuronide, and morphine-3-glucuronide in the isolated perfused rat kidney Drug Metabolism and Disposition: the Biological Fate of Chemicals 19(6): 1087-1092
Van Lancker, P.; Mortier, E.; Pieters, A.; Rolly, G. 1995: Evaluation of morphine for patient controlled analgesia with the Infusor system after opiate-free locoregional anesthesia for osteotomy of the foot Acta Anaesthesiologica Belgica 46(3-4): 113-120
Nehmad, R.; Nadler, H.; Simantov, R. 1982: Effects of acute and chronic morphine treatment of calmodulin activity of rat brain Molecular Pharmacology 22(2): 389-394
Yamamoto, H.; Harris, R.A.; Loh, H.H.; Way, E.L. 1978: Effects of acute and chronic morphine treatments on calcium localization and binding in brain Journal of Pharmacology and Experimental Therapeutics 205(2): 255-264
Davis, W.M.; Khalsa, J.H. 1973: Morphine lethality in rats: effects of inhibitors of brain catecholamine synthesis and methylation Research Communications in Chemical Pathology and Pharmacology 6(3): 867-872