Neuroaxonal dystrophy with delayed onset and protracted course

Mrůzek, M.; Stĕrba, J.; Kalousková, A.

Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 119(6): 481-487

1975


ISSN/ISBN: 0044-4030
PMID: 1210837
Document Number: 87888
An unusual case of neuraxonal dystrophy in a 24-year-old man has been described. The condition started at the age of 10 years with motoric disturbances, later the patient developed spastic quadruparesis and deep dementia in last two years. The disease appears to be of genetic origin. The morphology is characterized by the generalized presence of spheroids in the central nervous system. Additional findings of status pigmentosus and dysmyelinisatus do not exclude the case from being labelled neuraxonal dystrophy.

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