Drug-resistant salmonellosis
Kundu, A.K.
Journal of the Indian Medical Association 103(6): 327-331
2005
ISSN/ISBN: 0019-5847 PMID: 16225159 Document Number: 8745
After the development of plasmid-mediated resistance against first-line drugs, the emergence of chromosomally-mediated quinolone resistance in typhoid fever has become a major concern. Quinolone insensitivity and treatment failures with ciprofloxacin are being increasingly reported. However, third generation cephalosporins have come as a saviour. To overcome fluoroquinolone insensitivity, higher doses with longer duration of treatment is recommended. Moreover, return of chloramphenicol and furazolidone sensitivity shown by different studies is a welcome observation.
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