Comparison of Automated ACMIA and EMIT Immunoassays for Whole Blood Cyclosporin Monitoring

Dessars, B.; Frédéric Cotton; Thiry, P. and Béatrice Gulbis

Clinical Laboratory 49(3-4): 135-140

2003


ISSN/ISBN: 1433-6510
PMID: 12705695
Document Number: 8558
Objective: Evaluation of a new fully automated antibody conjugated magnetic immunoassay (ACMIA) for whole blood cyclosporin (CsA) monitoring. Method: Evaluation of the analytical performance of the ACMIA method and comparison to the Enzyme Multiplied Immunoassay (EMIT) method. Results: The analytical performance of the ACMIA and the EMIT methods was comparable. Without the need of a pretreatment step of the sample, the ACMIA method is faster than the EMIT method. Conclusion: The ACMIA method for CsA monitoring is a good alternative to the EMIT method.

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Comparison of Automated ACMIA and EMIT Immunoassays for Whole Blood Cyclosporin Monitoring