Comparative clinical effectiveness of cough medication

Cass, L.J.; Frederik, W.S.

American Practitioner and Digest of Treatment 2(10): 844-851

1951


ISSN/ISBN: 0097-658X
PMID: 14885632
Document Number: 8545
1. Fifty-two institutionalized tubercular patients, having in common the symptom cough, served as subjects to evaluate the acceptability and effectiveness of three expectorant drugs; (1) Robitussin, (2) terpin hydrate and (3) ammonium chloride. 2. Series of observations were made daily on the patients under treatment with each medication and rated numerically for the purpose of statistical analysis of data. 3. In all important categories the glyceryl guaiacolate preparation (Robitussin) was significantly superior to the other preparations studied. 4. It is believed that the greater effectiveness and patient-acceptance of the glyceryl guaiacolate preparation is a reflection of its most marked activity in increasing respiratory tract secretions (Respiratory Tract Fluid).

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Comparative clinical effectiveness of cough medication