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The therapeutic application of end-expiratory pressure in the meconium aspiration syndrome

Fox, W.W.; Berman, L.S.; Downes, J.J.; Peckham, G.J.

Pediatrics 56(2): 214-217

1975

ISSN/ISBN: 0031-4005
PMID: 1099523
Document Number: 84905
The effectiveness of end-expiratory pressure (EEP) in relieving hypoxemia in the meconium aspiration syndrome (MAS) was studied in 14 patients with the disorder. These infants demonstrated a direct, mean PO2 response of 12 torr/cm H2O EEP. A maximum PO2 response was observed in an EEP range of 4 to 7 cm H2O. EEP was equally effective whether patients were breathing spontaneously or were being mechanically ventilated. EEP is useful in the treatment of hypoxemia in the infants with meconium aspiration syndrome.

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