Amyloid fibril protein related to immunoglobulin lambda-chains

Skinner, M.; Benson, M.D.; Cohen, A.S.

Journal of Immunology 114(4): 1433-1435

1975


ISSN/ISBN: 0022-1767
PMID: 804011
Document Number: 84449
Amyloid fibrils, isolated from the spleen of a patient with primary amyloidosis, had an N-terminal sequence showing a high degree of homology with lambda Bence Jones proteins. Anti-serum prepared to the amyloid protein detected a soluble factor, antigenically identical to the isolated fibril preparation.

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