The effect of pharmacologic substances on intraspecies aggression
Burov, I.V.; Salimov, R.M.
Biulleten' Eksperimental'noi Biologii i Meditsiny 79(5): 64-67
1975
ISSN/ISBN: 0365-9615 PMID: 1241663 Document Number: 84445
It is found, that aggression which occures in rats under inevitable painful stimulation is coursed as excessive excitation of the rats. This aggression may be used for revealing the sedative effect of drugs. The method of fighting for the stool which is caused by motivated fighting for the territory was worked out. This motivated aggression may be used for revealing the tranquillizing effect of drugs. Using these methods it is found that stelasine, haloperidol, amitriptyline, imipramine, chlordiazepoxide, diazepam and benactyzine in small doses have a tranquillizing effect, while pentobarbital and chlorpromazine have primarily a sedative effect.