Glomerular lesions in Hodgkin disease
Yum, M.N.; Edwards, J.L.; Kleit, S.
Archives of Pathology 99(12): 645-649
1975
ISSN/ISBN: 0363-0153 PMID: 1203035 Document Number: 84414
Three cases of Hodgkin disease with renal manifestations were studied with electron microscopy and immunofluorescence. The first patient had lipoid nephrosis that disappeared after chemotherapy for Hodgkin disease. Immune-complex nephritis was observed in the second patient who also had Sjogren syndrome. The third patient developed amyloid nephrosis five years after the onset of Hodgkin disease. Apparently, diverse lesions and mechanisms are involved in the development of the nephrotic syndrome in Hodgkin disease and the diagnosis can only be established by appropriate studies of kidney specimens.