Base pair substitutions induced by Escherichia coli K-12 mutator gene prv
Khmel'nitskiĭ, M.I.; Zlotnikov, K.M.
Genetika 11(8): 81-87
1975
ISSN/ISBN: 0016-6758 PMID: 767212 Document Number: 84096
Using the trpA system of Yanofsky, it is shown that the mutator gene prv of Escherichia coli K-12 induces transitions in both directions (A:T in equilibrium G:C), and not A:T leads to leads to C:G and C:G leads to A:T transversions. The prv1 mutation was found to be recessive in prv+/prv1 merodiploid.
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