Synthesis and properties on some 2-, 4- and 5-aminopyrimidines. Effect of -NH2 and ortho-C methylation on protolytic equilibria and electronic absorption spectra
Proba, Z.; Wierzchowski, K.L.
Acta Biochimica Polonica 22(2): 131-142
1975
ISSN/ISBN: 0001-527X PMID: 239509 Document Number: 84004
A number of new 2-, 4- and 5-aminopyrimidines with sterical hindrance to the amino group rotation were synthesized. The pKa values and u.v. absorption spectra of the aminopyrimidines were measured in order to elucidate the conformation of the amino group depending on the place of substitution.