Marked prolongation of skin homograft survival with niridazole. A first report
Mandel, M.A.; Mahmoud, A.A.; Warren, K.S.
Plastic and Reconstructive Surgery 55(1): 76-89
1975
ISSN/ISBN: 0032-1052 PMID: 1089984 Document Number: 83882
Niridazole, a nitroheterocyclic drug used to treat helminth infections is reported for the first time to suppress cell-mediated immunity, as ascertained by multiple in vivo assays. Skin homograft survival time was significantly prolonged in mice, without loss of animals due to drug toxicity.
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