2 types of oncornavirus viroins in epithelial cells from human milk
Miller, G.G.; Kriukova, I.N.; Mazurenko, N.N.; Zhdanov, V.M.
Voprosy Virusologii 1975(4): 429-434
1975
ISSN/ISBN: 0507-4088 PMID: 175579 Document Number: 82913
Virions of types B and C similar to previously known mammalian oncornaviruses were found in tissue cultures prepared from epithelial cells sedimented from the milk of a lactating woman with mammary cancer (HEC-31) and the milk of 2 clinically normal women (HEC-33 and HEC-34). In HEC-33 culture type C particles were quantitatively predominant. All 3 milk specimens gave an identical precipitation line with antiserum the milk of the mammary cancer patient, and contained sequences forming molecular hybrids with oncornavirus type D DNA. No positive immunologic reaction was obtained with the test system for oncornavirus type D from HEp-2 cells.