Localization of the ruthenium red-positive substance in the myoneural junction of rat
Kovács, A.
Acta Biologica Academiae Scientiarum Hungaricae 26(3-4): 209-216
1975
ISSN/ISBN: 0001-5288 PMID: 62480 Document Number: 82847
Ruthenium red staining of myoneural junctions was examined in the flexor digitorum brevis muscle of the rat. Ruthenium red-positive electron dense substance was observed to emerge from the outer layer of the presynaptic axolemma and post-synaptic sarcolemma towards the synaptic cleft. Also the cleft substance was intensely stained, usually consisting of a medium dense layer between pre- and postsynaptic membranes. The probable function of acid mucopolysaccharides in the neuromuscular transmission is discussed.