Serum Erythropoietin Concentrations in Patients with Anemia - Preliminary Hemoglobin-Related Reference Ranges
Vogeser, M.; Schiel, X.
Clinical Laboratory 48(11-12): 595-598
2002
ISSN/ISBN: 1433-6510 PMID: 12465743 Document Number: 7609
Serum erythropoietin (EPO) determination is useful in the diagnosis of renal anemia. In anemic patients with normal renal function increased EPO concentrations are typically found, however, so far hemoglobin-related reference ranges for serum EPO had not been established. In a cross-sectional manner we determined serum EPO in 280 patients with anemia and normal serum concentrations of creatinine and urea. Each 70 consecutive anemic patients with hemoglobin concentrations within four intervals were included ( nd IRP 67/343. The ranges between the 20 th and 80 th percentile of EPO concentrations for the four specified hemoglobin intervals were as follows: Hb th percentile of EPO concentrations as a preliminary hemoglobin-related reference range; serum EPO concentrations below this percentile speak for a contribution of EPO deficiency in the individual etiology of anemia. (Clin. Lab. 2002;48:595-598) DOI: Clin. Lab. 2002;48:595-598
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