Plasma concentration after instilling 2% lignocaine gel into the urethra
Mets, B.; von Oppell, U.O.
South African Medical Journal 83(2): 134-135
1993
ISSN/ISBN: 0256-9574 PMID: 8451695 Document Number: 7340
This report serves to highlight that significant absorption of lignocaine occurs through the urethral mucosa and that subsequent therapeutic levels of lignocaine are maintained for a prolonged period. We suggest that where a lubricant is required for urethral catheterisation under general anaesthesia an alternative to a lignocaine-containing jelly be sought. Furthermore, we urge pharmaceutical companies to make a urethral gel containing a more appropriate lower concentration of lignocaine - 1% lignocaine gel - available in South Africa.
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