Metastatic lymphoepithelioma to the orbit: an aggressive rare nasopharygeal tumor in a Hispanic patient
Calderón Alicea, E.; Santiago-Casiano, M.ón.; Cáceres-Perkins, W.; Almodovar, A.
Boletin de la Asociacion Medica de Puerto Rico 104(4): 37-40
2012
ISSN/ISBN: 0004-4849 PMID: 23763221 Document Number: 702504
A 64 year-old Hispanic male patient presented to our institution with a three-month history of frontal headaches, reduced vision, retroorbital pain, photophobia, sinus congestion, bloody nasal discharge, and decreased audition in the left ear. The diagnosis of metastatic lymphoepithelioma to the orbit was made based on clinical history, histopathological examination of an orbital biopsy, and imaging studies. Lymphoepithelioma rarely develops in Hispanic populations. However, it is endemic in certain areas, including North Africa, Southeast Asia. China and the far north hemisphere. Radiotherapy is th treatment of choice of localized lymphoepithelioma and concurrent chemotherapy-radiotherapy with neoadjuvant chemotherapy has been used in locally advanced metastatic settings.