Hepatic function, histopathology and biliary flora alterations in chronic cholecystitis
Ramírez, M.; Blasini, M.; Rosselló, P.J.
Boletin de la Asociacion Medica de Puerto Rico 74(10): 295-297
1982
ISSN/ISBN: 0004-4849 PMID: 6963891 Document Number: 701136
We studied the frequency and severity of liver damage as measured by histopathologic changes and alterations in hepatic functional tests, and the prevalence and composition of bacterial growth in bile, in 162 patients with chronic cholecystitis. Twenty three percent of bile cultures were positive. If likely contaminants are disregarded, the positive rate for bile cultures becomes 13.3%. There was fatty infiltration in 42% of liver biopsies obtained, but most were minimal changes. Functional liver abnormalities were noted in approximately 20% of cases studied. We find therefore that there is a significant number of hepatic and biliary alterations in this group of patients undergoing elective cholecystectomy, but that these changes are minimal in magnitude.
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