Essential thrombocythemia: a hypercoagulable state

Hunter Mellado, R.F.; Oppenheimer Catalá, J.; Vázquez Medina, J.

Boletin de la Asociacion Medica de Puerto Rico 83(10): 436-439

1991


ISSN/ISBN: 0004-4849
PMID: 1789889
Document Number: 700401
Essential thrombocythemia is an entity characterized by clonal proliferation of megakaryocytes and thrombocytosis. We have analyzed the presenting manifestation of 13 patients with Essential Thrombocythemia diagnosed in the last three years. The major findings include the frequent presence of symptomatology of a hypercoagulable state with prompt improvement of these symptoms once the thrombocytosis is controlled. Constitutional symptoms, organomegaly, modest Leukocytosis and eosinophilia were also often seen. No catastrophic events were detected with a mean follow up period of 17.5 months.

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Essential thrombocythemia: a hypercoagulable state