Clinicopathological Study of 15 Cases of Primary Duodenal Cancer
Oshima, K.; Noguchi, K.; Tomimaru, Y.; Nagase, H.; Ogino, T.; Hirota, M.; Oshima, K.; Tanida, T.; Noura, S.; Imamura, H.; Akagi, K.; Iwazawa, T.; Dono, K.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 46(2): 354-356
2019
ISSN/ISBN: 0385-0684 PMID: 30914558 Document Number: 699537
There have been few reports discussing treatments for primary duodenal cancer. In this study, 15 cases of primary duodenal cancer that were treated by curative resection in our hospital between April 2005 and December 2017 were analyzed to study appropriate operative procedures. Prognostic analysis revealed that the median of relapse-free survival and overall survival were 49 months and 74 months, respectively. The 5-year survival rate was 47%. On univariate analysis of relapse-free survival, lymph node metastasis(p<0.01)and post-operative adjuvant therapy(p=0.02)were significant independent prognostic factors. Analysis of the relationship between lymph node metastasis and the depth or location of tumors suggested that pancreaticoduodenectomy with lymph node dissection should be performed to achieve radical resection, since there were some cases that involved lymph node metastasis around the pancreatic head or hepatoduodenal ligament.