A Case of Esophageal Primary Malignant Melanoma that Developed During the Follow-Up of Esophageal Melanocytosis
Yamai, D.; Ichikawa, H.; Kano, Y.; Hanyu, T.; Ishikawa, T.; Usui, K.; Nemoto, M.; Hirose, Y.; Miura, K.; Nagahashi, M.; Shimada, Y.; Sakata, J.; Kobayashi, T.; Kameyama, H.; Wakai, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 46(13): 2012-2014
2019
ISSN/ISBN: 0385-0684 PMID: 32157043 Document Number: 699506
A 78-year-old woman was endoscopically followed up for benign melanocytosis in the middle thoracic esophagus that was detected 3 years prior. She presented with chest tightness, and an endoscopic examination revealed a protruding tumor at the melanotic lesion. She was histologically diagnosedwith an esophageal primary malignant melanoma. Computedtomography showedno metastatic lesions. She underwent minimally invasive esophagectomy with 2-fieldlymphad enectomy. Immunotherapy with nivolumab is ongoing for liver metastasis, which developed1 year and6 months after esophagectomy. Careful follow-up for esophageal melanocytosis is important for early diagnosis of esophageal primary malignant melanoma.