Retrospective Analysis of Chronic Hepatitis C Patients with Hepatic Iron Depletion
Aziz, H.A.
Annals of Clinical and Laboratory Science 49(3): 380-384
2019
ISSN/ISBN: 0091-7370 PMID: 31308039 Document Number: 699415
The study retrospectively analyzed the effects of hepatic iron depletion on the therapy of chronic hepatitis C patients. A total of 195 patients from Hamad General Hospital were studied retrospectively. Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), and g-glutamyl transferase (GGT) tests were implemented; descriptive analysis and mean testing were performed to analyze the data. It has been observed that ferritin increases with HCV, displaying R-value =0.450 and p-value=0.182. Levels of ALT (P-value=0.812) and GGT (P-value=0.723) may increase slightly with the treatment. Chronic hepatitis C patients develop iron deficiency that can be marked by evaluating various iron markers in the body. The study identified that iron markers may decrease markedly among HCV patients; yet, researches consider the occurrence as support to management modality to improve response, delivered towards the treatment.