Ectopic ACTH-secreting neuroendocrine tumor: a rare etiology of a pediatric solid renal mass

Kocher, N.J.; Loloi, J.; Warrick, J.; Burns, A.S.; Decter, R.M.

Canadian Journal of Urology 26(5): 9956-9959

2019


ISSN/ISBN: 1195-9479
PMID: 31629447
Document Number: 699205
Neuroendocrine tumors (NETs) are rare tumors with varying clinical presentations. We describe the case of an 11-year-old female presenting with Cushingoid features in the setting of a left-sided flank mass. Her presentation and evaluation suggested a paraneoplastic ectopic ACTH syndrome. She underwent open left radical nephrectomy and final pathology confirming a high-grade NET with nodal metastasis. Although exceedingly rare, ACTH-secreting tumors of the kidney can cause significant morbidity and mortality and so we recommend it be included in the differential diagnosis of pediatric renal masses.

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