Movement Disorder and Epilepsy in Subependymal Nodular Heterotopia
Lohmror, A.; Choudhary, R.
Journal of the Association of Physicians of India 67(7): 11-12
2019
ISSN/ISBN: 0004-5772 PMID: 31559780 Document Number: 698123
Subependymal nodular heterotopia is a cortical development malformation that is commonly associated with refractory epilepsy. Patients with heterotopia show a wide spectrum of clinical manifestations, from being asymptomatic to presenting with intractable seizures and intellectual impairment. We report a case of refractory epilepsy with normal intelligence, having bilateral subependymal heterotopic nodules in brain, presenting to us with a movement disorder in the form of myoclonus of bilateral lower limbs which is an unusual manifestation of gray matter heterotopias. Though rare, gray matter heterotopias may present as movement disorder and should be considered in differential diagnosis while work up of movement disorders.