Genetic polymorphisms in benign prostatic hyperplasia: Progress in studies
Fan, G.-R.; Yang, E.-G.; Gao, S.-Z.; Wang, Z.-P.
Zhonghua Nan Ke Xue 25(10): 934-938
2019
ISSN/ISBN: 1009-3591 PMID: 32233227 Document Number: 698046
BPH is a common and frequently-occurring disease of the urinary system. The single nucleotide polymorphism (SNP) is the most common mutation in the genome and has an impact on the pathogenesis, progression and prognosis of BPH in different populations. We reviewed the published literature on BPH-related SNPs, expounded the roles of different SNPs in the development and progression of BPH, and summarized the current status and existing problems in the related studies and the prospects of its clinical application.