Top Abstract Purchase Related
Home
>
Node
>
Subnode

Sequential treatment with Mitomycin C and BCG in non muscle invasive bladder cancer

Chantada-Abal, V.; Chantada-Tirado, C.; Lamas-Díaz, L.; Caramés-Masana, F.; Villegas-Piguave, A.D.án.; Villar-Vázquez, N.

Archivos Espanoles de Urologia 71(4): 453-457

2018

ISSN/ISBN: 0004-0614
PMID: 29745935
Document Number: 697227
Bacilus Calmette-Guerin (BCG) administered intravesical is an effective therapy in non muscle invasive bladder cancer (NMIBC), but it presents limitations regarding recurrence and toxicity. For years, many case series have been published where sequential therapy with BCG and Mitomycin C (MMC) was tried. In this article, we perform a review of the data supplied by these articles with the aim to determine the safety and efficacy of combination, and what is the group of patients it should be indicated. Many studies show that combination therapy did not cause more toxicity and improved the interval free of disease with decrease of tumor progression compared to BCG or MMC monotherapy. Therefore, a combination of MMC and BCG therapy seems safe, but more clinical studies are required for a future evaluation.

Document emailed within 1 workday
Secure & encrypted payments

Ericson, K.J.; Murthy, P.B.; Bryk, D.J.; Ramkumar, R.R.; Broughman, J.R.; Khanna, A.; Mian, O.Y.; Campbell, S.C. 2019: Bladder-sparing treatment of nonmetastatic muscle-invasive bladder cancer Clinical Advances in Hematology and Oncology: H&o 17(12): 697-707
Kikuchi, E.; Oya, M. 2014: II. Urothelial carcinoma-current topics and treatment for non-muscle invasive bladder cancer- Gan to Kagaku Ryoho. Cancer and ChemoTherapy 41(1): 42-46
Izawa, J.I.; Chin, J.L.; Winquist, E. 2006: Timing cystectomy and perioperative chemotherapy in the treatment of muscle invasive bladder cancer Canadian Journal of Urology 13(Suppl 3): 48-53
Miyazaki, J. 2018: IIi .Current Status of Bladder Preservation Therapy for Muscle Invasive Bladder Cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 45(1): 33-37
Cao, M.; Ma, C.-k.; Ma, J.; Chen, H.-g.; Xue, W. 2011: Evaluation of the efficacy and safety of intravesical instillation with gemcitabine after first-line intravesical chemotherapy failure in the treatment of non-muscle-invasive bladder cancer Zhonghua Zhong Liu Za Zhi 33(5): 385-387
Henry, N.L.; MacVicar, G.; Hussain, M. 2005: Management of patients with muscle-invasive and metastatic bladder cancer Oncology 19(10): 1333-1342; Discussion 1342 1347 1350 Passim
Tian, Y. 2012: Attach importance to the chemotherapy of muscle invasive bladder cancer Zhonghua Yi Xue Za Zhi 92(6): 363-365
Tannock, I.F. 1990: Endpoints of clinical trials for muscle-invasive bladder cancer Progress in Clinical and Biological Research 353: 65-74
Gontero, P.; Fiorito, C.; Lucca, I.; Valentino, F.; Tizzani, A. 2008: New drugs currently available in non-muscle invasive bladder cancer: update on gemcitabine studies Archivio Italiano di Urologia Andrologia: Organo Ufficiale di Societa Italiana di Ecografia Urologica e Nefrologica 80(4): 162-166
Krijnen, P.; Bos, M.M.E.M.; Kloosterman-Boele, W.M.; Bevers, R.F.M. 2011: Variations in the treatment of non-metastatic muscle-invasive bladder carcinoma Nederlands Tijdschrift Voor Geneeskunde 155: A2703
Soloway, M.S. 1990: Follow up of patients receiving treatment for superficial bladder cancer with mitomycin C and BCG Progress in Clinical and Biological Research 350: 71-79
Boscolo-Berto, R.; Viel, G.; Lamon, C.; Agostini, A.; Vezzaro, R.; Gardiman, M.; Montisci, M.; Raduazzo, D.I. 2011: Giant scrotal lymphedema as unique onset sign of muscle-invasive bladder cancer. the risk of a misdiagnosis Archivio Italiano di Urologia Andrologia: Organo Ufficiale di Societa Italiana di Ecografia Urologica e Nefrologica 83(2): 95-98
Kida, K.; Shimizu, Y.; Ogawa, K.; Kanamaru, S.; Ito, N. 2018: Distant Metastasis in Patients with Non-Muscle Invasive Bladder Cancer without Local Recurrence : Report of Two Rare Cases Hinyokika Kiyo. Acta Urologica Japonica 64(6): 271-275
Boccon-Gibod, L.; Olier, C.; Debré, B.; Eschwege, F.; Steg, A. 1979: Infiltrating bladder cancer: is sequential radio-surgical treatment justified? Journal d'Urologie et de Nephrologie 85(6): 421-424
Sanjo, H.; Ito, Y.; Osaka, K.; Komiya, A.; Kobayashi, K.; Sakai, N.; Noguchi, S.; Kishi, H. 2012: Metastatic micropapillary variant of the urinary bladder: progression from low grade non-muscle invasive bladder carcinoma Hinyokika Kiyo. Acta Urologica Japonica 58(8): 447-451
Punga-Maole, M.L.; Hubert, J.; Mangin, P. 1995: Bladder retraction, a complication of chemoprophylaxis of superficial bladder cancer using intravesical mitomycin C. Apropos of a case and review of the literature Progres en Urologie: Journal de l'Association Francaise d'Urologie et de la Societe Francaise d'Urologie 5(4): 580-585
Ohtani, M.; Kakizoe, T.; Nishio, Y.; Sato, S.; Sugimura, T.; Fukushima, S.; Niijima, T. 1986: Sequential changes of mouse bladder epithelium during induction of invasive carcinomas by N-butyl-N-(4-hydroxybutyl)nitrosamine Cancer Research 46(4 Part 2): 2001-2004
Arnold, E.P.; Bailey, C.; Burry, A.F.; Bydder, P.V.; Firth, L.A.; Gowland, S.; Gray, A.J.; Mcllroy, R. 1981: A national trial on the treatment of invasive bladder cancer New Zealand Medical Journal 93(682): 273-275
Shaplygin, L.V.; Sitnikov, N.V.; Furashov, D.V.; Dronov, V.I.; Deviatov, A.S.; Sidorov, V.A. 2003: Radical cystectomy in the treatment of invasive bladder cancer Voenno-Meditsinskii Zhurnal 324(12): 43-46
Held, J.; Volpe, H. 1991: Bladder preserving combined modality therapy for invasive bladder cancer Oncology Nursing Forum 18(1): 49-57