Treatment Options for Amelobastic Carcinoma of the Mandible: A Case Series and Review of the Literature
Sheridan, G.A.; Nusrath, M.A.; Toner, M.; Stassen, L.Fa.
Irish Medical Journal 110(9): 639
2017
ISSN/ISBN: 0332-3102 PMID: 29372954 Document Number: 694547
We retrospectively review the only three cases in the Irish National Maxillofacial Unit over a 12-year period. Methods involved retrospectively reviewing clinical notes, radiology and histopathology of three cases. Case one was an 80-year-old male presenting with mandibular swelling, who received radiotherapy alone. Case two was a 26-year-old male with swelling and odynophagia. He underwent left hemimandibulectomy and fibular free flap reconstruction. Case three was a 64-year-old female with mental nerve involvement who underwent a right hemimandibulectomy. The cases presented here illustrate a diverse sample regarding patient demographics and management approaches. Surgery usually necessitates en bloc resection, free flap reconstruction and 1-1.5 cm margins. Adjuvant radiotherapy may be required for close margins.