The biomarkers in medicine: search, choice, study and validation
Don, E.S.; Tarasov, A.V.; Epshtein, O.I.; Tarasov, S.A.
Klinicheskaia Laboratornaia Diagnostika 62(1): 52-59
2017
ISSN/ISBN: 0869-2084 PMID: 30615376 Document Number: 694137
The sphere of application of biomarkers is expanding every year and already comprises their using as indicator of presence or absence of disease, response to therapy, efficiency of medications or pre-clinical model of diagnostic parameter and even participant of process of search of mechanism of effect of medications. Hence, it is impossible to overestimate significance of studying of biomarkers. The article is dedicated to systematization and structuring of present information concerning biomarkers, starting from primary screening and completing with validation of chosen molecule or characteristic.