Fever and hypotension after treatment of syphilis; the Jarisch-Herxheimer reaction
Hendriks, K.D.; van Etten, R.W.; van Wijngaarden, P.
Nederlands Tijdschrift Voor Geneeskunde 161: D649
2017
ISSN/ISBN: 1876-8784 PMID: 28181892 Document Number: 693418
A 73-year-old man presented with fever and hypotension, which had developed a few hours after receiving treatment with benzyl-penicillin for secondary syphilis. These symptoms were due to the so-called Jarisch-Herxheimer reaction. The patient was admitted to hospital and treated with prednisone and intravenous fluids. Within 24 hours the patient had fully recovered. The symptoms, pathogenesis and treatment of Jarisch-Herxheimer reaction are discussed.
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