Investigation on reference ranges of thyroid hormones and urine iodine in early pregnancy
Wu, M.; Han, J.; Cai, J.; Zhang, H.; Hu, Y.; Shan, Y.; Ma, L.; Yang, L.; Yang, X.
Wei Sheng Yan Jiu 46(2): 287-290
2017
ISSN/ISBN: 1000-8020 PMID: 29903109 Document Number: 692813
To establish the reference ranges of serum thyroid hormones and urine iodine in early pregnancy. The study included 368 early pregnant women who underwent their routine antenatal care in Obstetric Clinic of Peking Union Medical College Hospital. The level of serum thyroid hormones was tested by automatic chemiluminescence immunoassay analyzer. The value of urine iodine was tested by inductively coupled plasma mass spectrometry. The reference ranges were decided by twoside limits( the 2. 5th and 97. 5th percentile values). The reference ranges of serum thyroid hormones in early pregnancy: FT3 3. 74- 5. 88 pmol/L, FT4 12. 54-20. 15 pmol/L, TSH 0. 12- 3. 48 mU/L. The reference ranges of individual urinary iodine concentration was 31- 543 μg/L. The reference ranges of serum thyroid hormones and individual urinary iodine in early pregnancy are established based on laboratory testing results.