Hope for chronic inflammatory diseases : the anti-IL-6 receptor monoclonal antibody tocilizumab
Spertini, F.ço.
Revue Medicale Suisse 13(544-545): 20-22
2017
ISSN/ISBN: 1660-9379 PMID: 28703529 Document Number: 692197
Certaines vasculites comme la maladie de Horton en particulier, certaines pathologies auto-inflammatoires (maladies de Behcet, de Still) imposent aux patients des traitements de longue durée par les stéroïdes et donc les exposent à des effets secondaires à long terme souvent inacceptables dans les formes résistantes. Depuis peu, quelques études contrôlées, prospectives sont venues soutenir l'intérêt de l'antirécepteur de l'IL-6 monoclonal dans ces pathologies, et laissent penser qu'il puisse prochainement devenir un traitement de seconde intention dans le Horton notamment.
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