Intravenous acetaminophen for the treatment of intrapartum fever and resolution of fetal tachycardia: a novel use for an old medication
Ope-Adenuga, S.; Burgess, A.P.H.; Reilly, J.G.; Moretti, M.; Lakhi, N.
Clinical and Experimental Obstetrics and Gynecology 44(1): 166-168
2017
ISSN/ISBN: 0390-6663 PMID: 29714893 Document Number: 692047
This case series demonstrates a potential new role for the use of intravenous (IV) acetaminophen. The authors reviewed two cases, whereby patients that developed intrapartum fever leading to fetal tachycardia were effectively treated with IV acetaminophen, leading to rapid reduction of maternal temperature and resolution of fetal tachycardia. Both patients had an uncomplicated vaginal delivery of healthy neonates. Intravenous acetaminophen, with its increased bioavailability and more rapid onset of action, may have benefit in the intrapartum setting by reducing adverse neonatal and maternal outcomes associated with febrile morbidity.