Evaluation of Anesthesia Method to Minimize Intraoperative Body Movement and Respiratory Depression for Dilatation and Curettage A Retrospective Study
Yamaguchi, S.; Kitamura, J.
Masui. Japanese Journal of Anesthesiology 65(11): 1166-1169
2016
ISSN/ISBN: 0021-4892 PMID: 30351806 Document Number: 691421
The optimal level of anesthesia and the dose of the agent to procure the least intraoperative body movement and respiratory depression have not been evaluated in dilatation of the cervix and curettage of the uterus (D & C). Sixty-eight patients were divided to one of the three groups. Group S: the use of sevoflurane (1-2%) [n=22]. Group 2.5 K: high dose (1.6-2.5 mg · kg(-1) of ketamine with fentanyl (50-100 μg) and midazolam (2 mg) [n=23]. Group 1.5 K: the standard dosage of ketamine (0.5-1.5 mg · kg(-1) with fentanyl (50-100 μg) and midazolam (2 mg) [n=23]. Patient's intraoperative body movement and the necessity of jaw-lift and assisted manual ventilation were evaluated. Intraoperative body movement was significantly higher in Group 1.5 than in Groups S or 2.5 K (P<0.05). Necessity of jaw-lift and assisted manual ventilation was significantly higher in Group S than in Groups 1.5 K or 2.5 K (P<0.05). Intravenous anesthesia using increasing doses of ketamine (1.6-2.5 mg · kg(-1) with fentanyl (50-100 μg) and midazolam (2 mg) reduces the intraoperative body movement without exacerbating respiratory depression during D&C.