Research progress on the cellular and molecular mechanisms of tooth eruption
Shiyan, H.; Nanquan, R.; Shuhao, X.; Xiaobing, L.
Hua Xi Kou Qiang Yi Xue Za Zhi 34(3): 317-321
2016
ISSN/ISBN: 1000-1182 PMID: 27526461 Document Number: 690523
Tooth eruption is a series of complicated physiological processes occurring once the crown is formed completely, as well as when the tooth moves toward the occasion plane. As such, the tooth moves through the alveolar bone and the oral mucosa until it finally reaches its functional position. Most studies indicate that the process of tooth eruption involves the alveolar bone, dental follicles, osteoclasts, osteoblasts, and multiple cytokines. Dental follicles regulate both resorption and formation of the alveolar bone, which is required for tooth eruption. Furthermore, root formation with periodontal ligament facilitates continuous tooth eruption. However, the exact mechanism underlying tooth eruption remains unclear. Hence, this review describes the recent research progress on the cellular and molecular mechanisms of tooth eruption.