Ascites is usually caused by an underlying liver cirrhosis. Salt restriction and diuretics is the basis for treatment
Schult, A.; Friis-Liby, I.
Lakartidningen 113
2016
ISSN/ISBN: 1652-7518 PMID: 26978810 Document Number: 690310
Ascites is a common complication of liver cirrhosis and is associated with a poor prognosis. The main pathophysiology is an increased portal pressure with compensatory activation of neurohumoral systems. A patient history, proper physical exam and adequate examination of ascitic fluid will reveal the aetiology in most cases. Complications such as spontaneous bacterial peritonitis and thrombosis of hepatic vessel should be excluded in cases of first episode of ascites or deterioration of ascites. A moderate salt restriction and treatment with diuretics is the mainstay of treatment. Potentially nephrotoxic drugs such as NSAID and ACE inhibitors should be avoided in patients with cirrhosis.