The laboratory diagnostic of patients with tuberculosis with medicinal resistance of agent
Popov, S.A.; Sabgaiida, T.P.; Mojokina, G.N.
Problemy Sotsial'noi Gigieny Zdravookhraneniia i Istorii Meditsiny 24(5): 272-276
2016
ISSN/ISBN: 0869-866X PMID: 29558087 Document Number: 689449
The article considers possibilities and means of transition to personalized treatment of patients with tuberculosis conditioned by fast development and spreading of medicinal resistance of tuberculosis agent. The technical possibilities are demonstrated for realization of this approach and also necessity of information possessing in the field of evaluation of treatment effectiveness. Also, attention was paid to relationship ofpharmacogenetics and pharmacokinetics of wide spectrum of anti-tuberculosis medications, medicinal resistance of agent and genetic conditioning of development of side-effect negative reactions to chemotherapy.