Diagnostic accuracy of Xpert MTB/RIF versus smear microscopy in the early diagnosis tuberculosis in the real life of "Umberto I" Hospital Rome
Sauzullo, I.; Rodio, D.M.; Facchinetti, S.; Puggioni, G.; De Angelis, M.; Goldoni, P.; Vullo, V.; Mengoni, F.; Trancassini, M.; Pietropaolo, V.
New Microbiologica 39(4): 304-306
2016
ISSN/ISBN: 1121-7138 PMID: 27551727 Document Number: 688878
Early diagnosis of tuberculosis (TB) is one of the primary challenges in curtailing the spread of TB. This study aimed to determine the diagnostic accuracy of Xpert MTB/RIF for the identification of M. tuberculosis in clinical specimens, and compare this to a microscopist's diagnostic performance. Xpert MTB/ RIF was positive in all specimens with culture-confirmed TB, giving a higher sensitivity than the smear microscopy (100% versus 63%). The use of the Xpert MTB/RIF, as part of routine assay, permits rapid diagnosis of TB and enables clinicians to start an effective treatment.