Understanding Caries from the Oral Microbiome Perspective
Tanner, A.C.R.; Kressirer, C.A.; Faller, L.L.
Journal of the California Dental Association 44(7): 437-446
2016
ISSN/ISBN: 1043-2256 PMID: 27514155 Document Number: 688825
Dental caries is a major disease of the oral cavity with profound clinical significance. Caries results from a transition of a healthy oral microbiome into an acidogenic community of decreased microbial diversity in response to excessive dietary sugar intake. Microbiological cultivation, molecular identification, gene expression and metabolomic analyses show the importance of the entire microbial community in understanding the role of the microbiome in the pathology of caries.