Current advance in saliva-derived exosome study
Zhao, Y.; Yin, L.Y.; Bi, R.R.; Ma, P.; Li, S.B.
Zhonghua Kou Qiang Yi Xue Za Zhi 51(12): 765-769
2016
ISSN/ISBN: 1002-0098 PMID: 27978919 Document Number: 688818
There is growing interest in the whole saliva as a diagnostic fluid because of the relatively simple and non-invasive collection. Research on salivary proteomic and genomic has greatly facilitated the diagnosis and therapy of oral diseases, also revealed the molecular mechanism of the diseases. Saliva-derived exosome as a new source, with various molecular constituents of their cells of origin, including proteins, mRNA and miRNA might serve as potential biomarker. This article reviews the biological properties of saliva exosome, its separation and other aspects associated with disease.