Zollinger-Ellison syndrome: an unusual case of chronic diarrhoea in a child
Goyal, R.; Debi, U.; Dey, P.; Prasad, K.K.; Thapa, B.R.
Malaysian Journal of Pathology 38(3): 321-325
2016
ISSN/ISBN: 0126-8635 PMID: 28028304 Document Number: 687761
Most cases of Zollinger-Ellison syndrome (ZES) are described in adults. It is a rare disorder in childhood. Most cases present with abdominal pain due to peptic ulceration and chronic diarrhoea not responding to general measures. The symptom complex is initially confused with other more common diseases, which lead to a delay in diagnosis. We present a rare case of a-12-year boy who initially presented with abdominal pain, diarrhoea, vomiting and progressive weight loss for over a two-year period before he was finally diagnosed as a case of ZES with the primary tumour in the pancreatic head and with multiple metastasis in both the liver and lymph nodes.