Two Cases of Krukenberg Tumors that Metastasized from Gastric Cancer Treated with Multidisciplinary Therapy
Namikawa, T.; Fujisawa, K.; Munekage, E.; Munekage, M.; Shiga, M.; Maeda, H.; Kitagawa, H.; Nagata, Y.; Kumon, M.; Kobayashi, M.; Hanazaki, K.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 43(12): 2211-2212
2016
ISSN/ISBN: 0385-0684 PMID: 28133272 Document Number: 687075
A 34-year-old woman underwent total gastrectomy with D2 lymphadenectomy for gastric cancer, and the final diagnosis was T4N3M0, Stage III C, R0. Bilateral ovarian metastases were identified 51 months later, which were removed, and the patient received S-1 plus CDDP chemotherapy. Because the patient developed pubic bone metastasis 16 months after the second operation, we continued chemotherapy using paclitaxel with bisphosphonate. The patient was alive 70 months after the initial operation. The second patient was a 55-year-old woman who underwent total gastrectomy with D2 lymphadenectomy and was diagnosed with T2N2M0, Stage III A gastric cancer. Bilateral ovarian metastases were identified 72 months later, which were removed, and the patient received S-1 plus CDDP chemotherapy. The patient is alive with no signs of disease recurrence 96 months after the initial operation. For patients with ovarian metastases from gastric cancer, surgical resection in addition to chemotherapy might be an effective treatment. However, further studies and assessments of additional cases are needed to confirm the ideal treatment for this condition.