Life-Threatening Thrombo-embolic Events in a Case of Dengue Hemorrhagic Fever
Agarwal, A.; Sharma, S.; Airun, M.
Journal of the Association of Physicians of India 64(8): 87-89
2016
ISSN/ISBN: 0004-5772 PMID: 27762119 Document Number: 686477
In Dengue Hemorrhagic Fever (DHF), hemorrhagic manifestations are common but thrombotic events are uncommonly reported, despite the wide range of increased procoagulant activity during Dengue Fever illness. We report a case of a 55-year-old man of Asian Indian ethnicity who developed large vein thrombotic event -Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) in the acute phase of DHF. His condition was further complicated by associated thrombocytopenia. The etiological connections between dengue viral infection with thrombocytopenia, DVT/PE and abnormal thrombophilia profile as well as the treatment dilemmas posed in treating a patient of DF with hemorrhagic manifestations and associated DVT/PE, and the role of eltrombopag are discussed.