A new phenylacetamide from the seeds of Lepidium apetalum Willd
Meng, L.; Zheng, X.-k.; Zhang, Z.-g.; Zhang, J.-k.; Zhao, X.; Yang, Y.-y.; Wang, X.-l.; Kuang, H.-x.; Feng, W.-s.
Yao Xue Xue Bao 51(12): 1881-1884
2016
ISSN/ISBN: 0513-4870 PMID: 29908559 Document Number: 686239
The chemical constituents of the seeds of Lepidium apetalum Willd. were investigated using chromatographic methods, including Diaion HP-20, Toyopearl HW-40, MCI Gel CHP-20, ODS, silica gel chromatography and semi-preparative-HPLC. Three compounds were isolated and their structures were elucidated by spectral data and physicochemical properties, which were identified as lepidiumamide A (1), cis-desulfoglucotropaeolin(2), trans-desulfoglucotropaeolin (3). Among those, compound 1 is a new phenylacetamide, compound 2 and 3 were isolated from this plant for the first time, and their configurations were also identified for the first time.