Management of Sitagliptin and Metformin Combination Toxic Overdose
Sehra, S.; Jaggi, S.; Sehra, D.; Aggarwal, R.; Saraswat, V.; Juneja, D.
Journal of the Association of Physicians of India 64(11): 80-81
2016
ISSN/ISBN: 0004-5772 PMID: 27805342 Document Number: 686169
Metformin and Sitagliptin are often used in combination in the management of non-insulin dependent diabetes mellitus. Though toxicity is rare, but occurs more frequently in cases of intentional or unintentional overdose of these drugs. Here, we present a case of an intentional overdose of a metformin- sitagliptin combination (70g metformin and 3500mg sitagliptin) in a suicide attempt by a young non-diabetic female who presented with severe lactic acidosis and was successfully treated with prompt hemodialysis and bicarbonate therapy.
Document emailed within 1 workday
