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Effects of chronic hypokinetic stress on microhemodynamics of tissue

Chuyan, E.N.; Ravaeva, M.Y.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 101(3): 316-325

2015

ISSN/ISBN: 0869-8139
PMID: 26016325
Document Number: 685579
By laser Doppler flowmetry investigated tissue microhemodynamics rats kept hypokinesia under 10 days. Investigation of the structure of rhythms blood flow oscillations in microvasculature revealed that chronic hypokinetic stress leads to a significant reduction of the oscillator and nonoscillation microhemodynamics indicators, reflected in the development of vasoconstriction, reducing the metabolic function of the endothelium and the allocation to them of nitric oxide, a violation of inflow and outflow of blood, the dominance of shunt blood flow, decreasing the number of functioning capillaries.

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