The Need for Hbv Genotyping: a Cost-Efficient Approach
Luca, A.S.; Ursu, R.G.; Teuşan, T.; Luca, C.ăt.ăl.M.; Pleşca, C.E.; Iancu, L.ţa.S.
Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 119(4): 982-987
2015
ISSN/ISBN: 0048-7848 PMID: 26793838 Document Number: 685284
The outcome of chronic HBV infection is variable; approximately one half of individuals transition to an inactive carrier state, 30% progress to cirrhosis, and the remainder to chronic hepatitis. Ten different HBV genotypes and many subtypes have been identified with distinct geographical distributions. Over the years, a lot of studies presented the efficiency of different genotyping methods; for this reason we aimed to present a cost efficient genotyping diagnosis algorithm of CHB infected patients, especially useful to identify those at risk of disease progression and determine optimal anti-viral therapy as useful instrument for physicians.