Determination of total Bromine in urine by inductively coupled plasma mass spectrometry (ICP-MS)
Zhou, C.; Zhu, H.; Liu, D.; Miao, R.; Ying, L.; Zhu, B.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 33(5): 396-397
2015
ISSN/ISBN: 1001-9391 PMID: 26653245 Document Number: 685237
To establish a method to determine total bromine in urine. Diluted urine samples were directly introduced into ICP-MS then quantized by standard curve. Total bromine in urine was linear within 1.0~50 mg/L with r > 0.999, When spiked at a concentration of 0.020 mg/L, 0.050 mg/L, 0.150 mg/L, the recovery was 95%~98%, intra-assay precision was 1.4% 3.2%, inter-assay precision was 3.4% to 5.0%. Urine could store in -20 °C refrigerator 3 months without any bromine loss. Using ICP-MS to determine the urinary total bromine, the method is fast, accurate, wide linear range of features, could meet with the requirement of Part 5 of occupational health standards guide: Method determination of chemical substances in biological materials (GBZ/T 210.5-2008), a strong competitive advantage in a wide range of survey, suitable for promotion.