Analysis of Musculoskeletal Systems and their Diseases. Genomic medicine of bone and joint diseases : present and future
Ikegawa, S.
Clinical Calcium 25(8): 1125-1131
2015
ISSN/ISBN: 0917-5857 PMID: 26224668 Document Number: 685184
Susceptibility genes for various kinds of common diseases have been identified by the genome-wide association study (GWAS) and the outcome is changing the clinical medicine significantly. Musculoskeletal disease is no exception. In this paper, I review the current status and prospect of GWAS in musculoskeletal diseases in Japan by focusing on representative common musculoskeletal diseases : disc herniation, adolescent idiopathic scoliosis and ossification of the posterior longitudinal ligament of the spine.