Clinical Inquiry: Does qHPV vaccine prevent anal intraepithelial neoplasia and condylomata in men?
Shum, J.; Kelsberg, G.; Safranek, S.
Journal of Family Practice 64(9): 581-583
2015
ISSN/ISBN: 0094-3509 PMID: 26546954 Document Number: 684848
Yes. Quadrivalent human papillomavirus (qHPV) vaccine reduces rates of anal intraepithelial neoplasia (AIN) by 50% to 54%, and persistent anal infection by 59%, associated with the 4 types of HPV in the vaccine (6, 11, 16, and 18) in young men who have sex with men (MSM); it also reduces external genital lesions by 66%, and persistent HPV infection associated with the same 4 HPV types by 48 to 59% in all young men, heterosexual men, and MSM.
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